![]() ![]() “They can be detached, attached to another condensate, or completely embedded within one another. “Different condensates can coexist inside the cells,” says first author Taranpreet Kaur, a PhD student in physics in the UB College of Arts and Sciences. The project brought together a team from the University at Buffalo and Iowa State University. The research lays out physical rules controlling the arrangement of various types of synthetic MLOs created using just three kinds of building materials: RNA and two different proteins, a prion-like polypeptide (PLP) and an arginine-rich polypeptide (RRP). 8 in Nature Communications explores how these compartments, also known as membraneless organelles (MLOs) or biomolecular condensates, form and organize themselves. And these varying assemblies can regulate the functions the droplets perform.Ī study published on Feb. Other times, one droplet can be found nested inside of another. Instead, they take the form of liquid droplets that don’t have a membrane, forming spontaneously, similar to oil droplets in water. These compartments are akin to specialized rooms inside a house, but their architecture is radically different: They don’t have walls. ![]() In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.
0 Comments
Leave a Reply. |